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In contrast, derepression off ThPOK transcription for the DP thymocytes off ThPOKCD4.Sil rats decorative mirrors phrase out-of endogenous Cd4 during the DP thymocytes away from wt mice. Such as for example, this new SilThPOK prevents brand new transcription regarding Cd4 during the DP thymocytes out-of CD4ThPOK.Sil mice just as the suppression away from endogenous ThPOK within the DP thymocytes from wt rats. FACS studies off TCR?, CD69, CD4, and you will CD8 term out-of (b) overall thymocytes, gated thymocytes and you may (c) peripheral T-phone subsets off wt mice otherwise mutant contours, while the shown. Analytical benefit is computed for each and every expressed mutant range according to wt rats. FACS studies of TCR?, CD69, CD4, and you may CD8 term of complete thymocytes, gated thymocytes (c), and you may peripheral T-phone subsets (d) of wt mice otherwise mutant contours, once the shown.
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